Quantifying Small Changes in Brain Ventricular Volume Using Non-rigid Registration

Abstract. Non-rigid registration can automatically quantify small changes in volume of anatomical structures over time by means of segmentation propagation. Here we use a non-rigid registration algorithm based on optimising normalised mutual information to quantify small changes in brain ventricular volume in MR images of a group of ve patients treated with growth hormone replacement therapy and a control group of six volunteers. The lateral ventricles are segmented from each subject image by registering the brainweb image 1 which has this structure delineated. The mean standard deviation volume change measurements

• Type: Conference
• Year: 2001
• Where: MICCAI
• Authors: Mark Holden, Julia A. Schnabel, Derek L. G. Hill
• Keywords: Medical Imaging, MICCAI 2001, Non-rigid Registration, Non-rigid Registration Algorithm, Small Changes