Ribonuclease P is the endoribonuclease responsible for the removal of leader sequences from tRNA precursors. Ribonuclease P is a ribonucleoprotein, and in bacteria the RNA alone is capable of pre-tRNA processing in vitro, i.e. it is a catalytic RNA. The Ribonuclease P Database is a compilation of ribonuclease P sequences, sequence alignments, secondary structures, three-dimensional models and accessory information, in the form of a hypertext document available via the Worldwide Web.
James W. Brown