: Semantic technologies promise fully leveraging the content of enterprise and business process models by applying reasoning techniques to query the process space or using ontological mappings for bridging the business-IT divide. Such an approach is known as semantic business process management. We conducted an empirical case study to explore semantic business process management. The case study was replicated 13 times with 17 participants from 8 different industrial and scientific organisations following a strict case study methodology to ensure validity and reliability of the results. The results show that participants embrace the possibilities of semantic technologies, but there are still open problems. In this paper, we present the case study design and discuss the results achieved.