Shape analysis with multivariate tensor-based morphometry and holomorphic differentials

In this paper, we propose multivariate tensor-based surface morphometry, a new method for surface analysis, using holomorphic differentials; we also apply it to study brain anatomy. Differential forms provide a natural way to parameterize 3D surfaces, but the multivariate statistics of the resulting surface metrics have not previously been investigated. We computed new statistics from the Riemannian metric tensors that retain the full information in the deformation tensor fields. We present the canonical holomorphic one-forms with improved numerical accuracy and computational efficiency. We applied this framework to 3D MRI data to analyze hippocampal surface morphometry in Alzheimer's Disease (AD; 12 subjects), lateral ventricular surface morphometry in HIV/AIDS (11 subjects) and biomarkers in lateral ventricles in HIV/AIDS (11 subjects). Experimental results demonstrated that our method powerfully detected brain surface abnormalities. Multivariate statistics on the local tensors...

• Type: Journal
• Year: 2009
• Where: ICCV
• Authors: Yalin Wang, Tony F. Chan, Arthur W. Toga, Paul M. Thompson
• Keywords: Computer Vision, ICCV 2009, Multivariate Statistics, Multivariate Tensor-based Surface, Surface Morphometry