Keywords Name of the disease and synonyms Definition/Diagnostic criteria Juvenile form Comments on the differential diagnosis Incidence Clinical description Method of biological diagnosis Evolution Frequency of episodes of the disease Management/Treatments Etiology Genetic counseling References Adult onset Still's disease is a rare rheumatic condition. Its main feature is the combination of symptoms, such as fever higher than 39°C, cutaneous rash during fever peaks, joint or muscle pain, lymph node hypertrophy, increase of white blood cells (especially polymorphonuclear neutrophils) and abnormalities of liver metabolism. Other symptoms may also be present. None of these signs is sufficient to establish the diagnosis, and several other diseases (notably infectious or neoplastic diseases) may produce similar symptoms. Thus, adult onset Still's disease often corresponds to a « diagnosis of exclusion », meaning that the diagnosis is retained when the other possible diagnoses...