—Subspace-based blind and group-blind space-time multiuser detection is invoked for a smart antenna aided generalized MC DS-CDMA system communicating over a dispersive Space-Time (ST) Rayleigh fading channel, where the channel estimates are attained by using subspacebased blind techniques. In the generalized MC DS-CDMA system considered, smart antennas are employed, in order to provide increased degrees of freedom and hence to improve the attainable performance and user capacity. Furthermore, our simulation results confirm that in the proposed multiple antenna aided generalized MC DS-CDMA system, the blind and group-blind space-time multiuser detectors equipped with the subspacebased blind channel estimator are capable of achieving a similar performance to that exploiting the perfect knowledge of the channel.