Novel environments exploiting recent technology can enhance several tasks in applications such as mobile guides. However, in the many museum mobile guides that have been proposed, accessibility is often not explicitly addressed and the benefits of such technology are rarely made available to blind users. In this paper, we propose a solution for flexible orientation support in a multimodal and location-aware museum guide, which has been developed specifically for blind users. Keywords Mobile guides, sensing technology, accessibility, blind users. ACM Classification Keywords H5.m. Information interfaces and presentation (e.g., HCI).