act The strategic use of technology based information systems (IS/IT) is a fundamental issue for every business. This is particularly true in the case of firms that engage in international business activities. The present paper is part of an empirically oriented project to investigate the impacts of strategic alignment on organizational performance, especially in the case of European International Companies. We use Structural Equation Modeling to apprehend the strategic alignment concept as an emergent variable derived from the co variation of two components : (1) business strategy; and (2) the IS/IT strategy. Then, we explore the role of this emergent concept as a determinant of organizational performance. We use data from a large database constructed due to survey instruments to assess the usage of IS/IT among European firms. 505 questionnaires have been exploited in this study. The results obtained will be presented and discussed in this paper. Key-words: Strategic alignment, organi...