Abstract—Memetics is a new science that has attracted increasing attentions in the recent decades. Beyond the formalism of simple hybrids, adaptive hybrids and memetic algorithms, the notion of memetic automaton as an adaptive entity that is self-contained and uses memes as building blocks of information is recently conceptualized in the context of computational intelligence as potential tools for effective problem-solving [1]. Taking this cue, this paper embarks a study on Memetic Multiagent system (MeM) towards human-like social agents with memetic automaton. Particularly, we introduce a potentially rich meme-inspired design and operational model, with Darwin’s theory of natural selections and Dawkins’ notion of a meme as the principal driving forces behind interactions among agents, whereby memes formed the fundamental building blocks of the agents’ mind universe. Experimental studies on a Mine Navigation Task indicates the modeling of memetic agents that resemble the natura...