Towards an ontological representation of resistance: The case of MRSA

This paper addresses a family of issues surrounding the biological phenomenon of resistance and its representation in realist ontologies. Resistance terms from various existing ontologies are examined and found to be either overly narrow, inconsistent, or otherwise problematic. We propose a more coherent ontological representation using the antibiotic resistance in Methicillin-Resistant Staphylococcus aureus (MRSa) as a case study.

• Type: Journal
• Year: 2011
• Where: JBI
• Authors: Albert Goldfain, Barry Smith, Lindsay G. Cowell
• Keywords: Algorithms, Bioinformatics, Coherent Ontological Representation, JBI 2011, Methicillin-Resistant Staphylococcus Aureus, Various Existing Ontologies