Using feedback to regulate gene expression in a developmental control architecture

We present what we believe is the first attempt to physically reconstruct the exploratory mechanism of genetic regulatory networks. Feedback plays a crucial role during developmental processes and its mechanisms have recently become much clearer due to evidence from evolutionary developmental biology. We believe that without similar mechanisms of interaction and feedback, digital genomes cannot guide themselves across functional search spaces in a way that fully exploits a domain’s resources, particularly in the complex search domains of real-world physics. Our architecture is designed to let evolution utilise feedback as part of its mechanism of exploration. Categories and Subject Descriptors B.7 [Hardware]: Integrated Circuits General Terms Design Keywords Evolvable hardware, adaptation/self-adaptation, signal processing, gene regulatory networks, developmental processes

• Type: Conference
• Year: 2007
• Where: GECCO
• Authors: Kester Clegg, Susan Stepney, Tim Clarke
• Keywords: Developmental Processes, GECCO 2007, Genetic Regulatory Networks, Regulatory Networks