Using multiple tensor deflection to reconstruct white matter fiber traces with branching

The relationship between brain structure and complex behavior is governed by large-scale neurocognitive networks. Diffusion weighted imaging(DWI) is a noninvasive technique that can visualize the neuronal projections connecting the functional centers and thus provides new keys to the understanding of brain function. In this paper, we assume there are up to two diffusion channels at each voxel. A variational framework for 3D simultaneous smoothing and reconstruction of a multi-diffusion tensor field as well as a novel multi-tensor deflection(MTEND) algorithm for extracting white matter fiber traces based on the multi-diffusion tensor field are provided. By applying the proposed model to both synthetic data and human brain high angular resolution diffusion(HARD) magnetic resonance imaging(MRI) data of several subjects, we show the effectiveness of the model in recovering branching fiber traces. Superiority of the proposed model over existing models are also demonstrated.

• Type: Conference
• Year: 2006
• Where: ISBI
• Authors: Weihong Guo, Qingguo Zeng, Yunmei Chen, Yijun Liu
• Keywords: ISBI 2006, Large-scale Neurocognitive Networks, Medical Imaging, Multi-diffusion Tensor, fiber Traces