Voxel-based non-rigid registration algorithms have been successfully applied to a wide range of image types. However, in some cases the registration of quite different images, e.g. pre- and post-resection images, can fail because of a lack of voxel intensity correspondences. One solution is to introduce feature information into the voxel-based registration algorithms in order to incorporate higher level information about the expected deformation. We illustrate using one voxel-based registration algorithm that the incorporation of features yields considerable improvement of the registration results in such cases.
Thomas Hartkens, Derek L. G. Hill, Andy D. Castell