Abstract. With the availability of hundreds and soon-to-be thousands of complete genomes, the construction of genome-scale metabolic models for these organisms has attracted much a...
Immense amounts of raw instrument data (i.e., images of fluorescence) are currently being generated using ultra high-throughput sequencing platforms. An important computational cha...
A major source of information for identifying subcellular location on a proteome-wide basis will be imaging of tagged proteins in living cells using fluorescence microscopy. We ha...
Background: Probability based statistical learning methods such as mutual information and Bayesian networks have emerged as a major category of tools for reverse engineering mecha...
: A series of genome-scale algorithms and high-performance implementations is described and shown to be useful in the genetic analysis of gene transcription. With them it is possib...