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DESRIST
2009
Springer
109views Education» more  DESRIST 2009»
15 years 7 months ago
The constitutive and the instrumental in social design
Simon’s The Sciences of the Artificial is rightly influential as a founding text in design research in the information systems field (IS). Simon’s contributions in the same vo...
Murali Venkatesh
HIS
2007
15 years 3 months ago
Pareto-based Multi-Objective Machine Learning
—Machine learning is inherently a multiobjective task. Traditionally, however, either only one of the objectives is adopted as the cost function or multiple objectives are aggreg...
Yaochu Jin
BIBE
2010
IEEE
144views Bioinformatics» more  BIBE 2010»
15 years 3 months ago
Knowledge-Guided Docking of Flexible Ligands to SH2 Domain Proteins
Studies of interactions between protein domains and ligands are important in many aspects such as cellular signaling and regulation. In this work, we applied a three-stage knowledg...
Haiyun Lu, Shamima Banu Bte Sm Rashid, Hao Li, Wee...
GG
2008
Springer
15 years 3 months ago
Graph-Based Tools: The Contest
This event is the second instance of the contest for graph transformation-based tools, which was first held as part of the AGTIVE workshop. The aim is to stimulate tool developmen...
Arend Rensink, Pieter Van Gorp
BMCBI
2010
154views more  BMCBI 2010»
15 years 2 months ago
Binary image representation of a ligand binding site: its application to efficient sampling of a conformational ensemble
Background: Modelling the ligand binding site of a protein is an important component of understanding proteinligand interactions and is being actively studied. Even if the side ch...
Edon Sung, Sangsoo Kim, Whanchul Shin