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» A Comparison of Global and Local Search Methods in Drug Dock...
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BMCBI
2006
137views more  BMCBI 2006»
13 years 8 months ago
Bounded search for de novo identification of degenerate cis-regulatory elements
Background: The identification of statistically overrepresented sequences in the upstream regions of coregulated genes should theoretically permit the identification of potential ...
Jonathan M. Carlson, Arijit Chakravarty, Radhika S...
ICPR
2008
IEEE
14 years 3 months ago
Layered shape matching and registration: Stochastic sampling with hierarchical graph representation
To automatically register foreground target in cluttered images, we present a novel hierarchical graph representation and a stochastic computing strategy in Bayesian framework. Th...
Xiaobai Liu, Liang Lin, Hongwei Li, Hai Jin, Wenbi...
BMCBI
2006
194views more  BMCBI 2006»
13 years 8 months ago
Novel metaheuristic for parameter estimation in nonlinear dynamic biological systems
Background: We consider the problem of parameter estimation (model calibration) in nonlinear dynamic models of biological systems. Due to the frequent ill-conditioning and multi-m...
Maria Rodriguez-Fernandez, Jose A. Egea, Julio R. ...
BMCBI
2005
152views more  BMCBI 2005»
13 years 8 months ago
Improved profile HMM performance by assessment of critical algorithmic features in SAM and HMMER
Background: Profile hidden Markov model (HMM) techniques are among the most powerful methods for protein homology detection. Yet, the critical features for successful modelling ar...
Markus Wistrand, Erik L. L. Sonnhammer