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BMCBI
2004
134views more  BMCBI 2004»
13 years 8 months ago
Bayesian model accounting for within-class biological variability in Serial Analysis of Gene Expression (SAGE)
Background: An important challenge for transcript counting methods such as Serial Analysis of Gene Expression (SAGE), "Digital Northern" or Massively Parallel Signature ...
Ricardo Z. N. Vêncio, Helena Brentani, Diogo...
ECIR
1998
Springer
13 years 10 months ago
Evaluation of Interfaces for IRS: Modelling End-User Searching Behaviour
This paper describes an investigation in progress into the searching behaviour of end-users and how it is affected by interface design. The project focused on qualitative data gat...
Victoria Manglano, Micheline Beaulieu, Stephen E. ...
BMCBI
2006
160views more  BMCBI 2006»
13 years 9 months ago
Gene prediction in eukaryotes with a generalized hidden Markov model that uses hints from external sources
Background: In order to improve gene prediction, extrinsic evidence on the gene structure can be collected from various sources of information such as genome-genome comparisons an...
Mario Stanke, Oliver Schöffmann, Burkhard Mor...
BMCBI
2008
103views more  BMCBI 2008»
13 years 9 months ago
TOPS++FATCAT: Fast flexible structural alignment using constraints derived from TOPS+ Strings Model
Background: Protein structure analysis and comparison are major challenges in structural bioinformatics. Despite the existence of many tools and algorithms, very few of them have ...
Mallika Veeramalai, Yuzhen Ye, Adam Godzik
BMCBI
2005
135views more  BMCBI 2005»
13 years 8 months ago
A robust two-way semi-linear model for normalization of cDNA microarray data
Background: Normalization is a basic step in microarray data analysis. A proper normalization procedure ensures that the intensity ratios provide meaningful measures of relative e...
Deli Wang, Jian Huang, Hehuang Xie, Liliana Manzel...