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BMCBI
2004
207views more  BMCBI 2004»
13 years 7 months ago
Computational identification of transcription factor binding sites by functional analysis of sets of genes sharing overrep-resen
Background: Transcriptional regulation is a key mechanism in the functioning of the cell, and is mostly effected through transcription factors binding to specific recognition moti...
Davide Corà, Ferdinando Di Cunto, Paolo Pro...
TSP
2010
13 years 2 months ago
Selection policy-induced reduction mappings for Boolean networks
Developing computational models paves the way to understanding, predicting, and influencing the long-term behavior of genomic regulatory systems. However, several major challenges ...
Ivan Ivanov, Plamen Simeonov, Noushin Ghaffari, Xi...
CIBCB
2007
IEEE
13 years 12 months ago
Associative Artificial Neural Network for Discovery of Highly Correlated Gene Groups Based on Gene Ontology and Gene Expression
Abstract-- The advance of high-throughput experimental technologies poses continuous challenges to computational data analysis in functional and comparative genomics studies. Gene ...
Ji He, Xinbin Dai, Xuechun Zhao
CSB
2003
IEEE
124views Bioinformatics» more  CSB 2003»
14 years 1 months ago
SMASHing regulatory sites in DNA by human
Regulatory sequence elements provide important clues to understanding and predicting gene expression. Although the binding sites for hundreds of transcription factors are known, t...
Mihaela Zavolan, Nicholas D. Socci, Nikolaus Rajew...
BMCBI
2010
153views more  BMCBI 2010»
13 years 6 months ago
DiffCoEx: a simple and sensitive method to find differentially coexpressed gene modules
Background: Large microarray datasets have enabled gene regulation to be studied through coexpression analysis. While numerous methods have been developed for identifying differen...
Bruno M. Tesson, Rainer Breitling, Ritsert C. Jans...