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BMCBI
2011
13 years 2 months ago
The impact of quantitative optimization of hybridization conditions on gene expression analysis
Background: With the growing availability of entire genome sequences, an increasing number of scientists can exploit oligonucleotide microarrays for genome-scale expression studie...
Peter Sykacek, David P. Kreil, Lisa A. Meadows, Ri...
WOB
2004
134views Bioinformatics» more  WOB 2004»
13 years 9 months ago
Reconstruction of Phylogenetic Trees using the Ant Colony Optimization Paradigm
We developed a new approach for the reconstruction of phylogenetic trees using ant colony optimization metaheuristics.Atree is constructed using a fully connected graph and the pro...
Heitor S. Lopes, Mauricio Perretto
BICOB
2010
Springer
13 years 8 months ago
Integrative Biomarker Discovery for Breast Cancer Metastasis from Gene Expression and Protein Interaction Data Using Error-toler
Biomarker discovery for complex diseases is a challenging problem. Most of the existing approaches identify individual genes as disease markers, thereby missing the interactions a...
Rohit Gupta, Smita Agrawal, Navneet Rao, Ze Tian, ...
IMC
2005
ACM
14 years 1 months ago
Improving Sketch Reconstruction Accuracy Using Linear Least Squares Method
Sketch is a sublinear space data structure that allows one to approximately reconstruct the value associated with any given key in an input data stream. It is the basis for answer...
Gene Moo Lee, Huiya Liu, Young Yoon, Yin Zhang
BMCBI
2010
116views more  BMCBI 2010»
13 years 8 months ago
Predicting success of oligomerized pool engineering (OPEN) for zinc finger target site sequences
Background: Precise and efficient methods for gene targeting are critical for detailed functional analysis of genomes and regulatory networks and for potentially improving the eff...
Jeffry D. Sander, Deepak Reyon, Morgan L. Maeder, ...