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BMCBI
2006
94views more  BMCBI 2006»
13 years 7 months ago
Metabolite coupling in genome-scale metabolic networks
Background: Biochemically detailed stoichiometric matrices have now been reconstructed for various bacteria, yeast, and for the human cardiac mitochondrion based on genomic and pr...
Scott A. Becker, Nathan D. Price, Bernhard O. Pals...
NC
2010
150views Neural Networks» more  NC 2010»
13 years 6 months ago
Deterministic and stochastic P systems for modelling cellular processes
This paper presents two approaches based on metabolic and stochastic P systems, together with their associated analysis methods, for modelling biological systems and illustrates th...
Marian Gheorghe, Vincenzo Manca, Francisco Jos&eac...
BMCBI
2006
113views more  BMCBI 2006»
13 years 7 months ago
GibbsST: a Gibbs sampling method for motif discovery with enhanced resistance to local optima
Background: Computational discovery of transcription factor binding sites (TFBS) is a challenging but important problem of bioinformatics. In this study, improvement of a Gibbs sa...
Kazuhito Shida
COMPLIFE
2006
Springer
13 years 11 months ago
A New Approach to Flux Coupling Analysis of Metabolic Networks
Flux coupling analysis is a method to identify blocked and coupled reactions in a metabolic network at steady state. We present a new approach to flux coupling analysis, which uses...
Abdelhalim Larhlimi, Alexander Bockmayr
BMCBI
2004
154views more  BMCBI 2004»
13 years 7 months ago
Computation of elementary modes: a unifying framework and the new binary approach
Background: Metabolic pathway analysis has been recognized as a central approach to the structural analysis of metabolic networks. The concept of elementary (flux) modes provides ...
Julien Gagneur, Steffen Klamt