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» A Database Platform for Bioinformatics
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BIBE
2005
IEEE
126views Bioinformatics» more  BIBE 2005»
14 years 2 months ago
Suboptimal Alignments Improve the Detection of Weak Homologs in Sequence Database Searches
PSI-BLAST remains one of the popular tools for searching remote homologs in sequence databases. We recently demonstrated that hybrid alignment can function as the alignment core f...
Yuheng Li, Mario Lauria, Ralf Bundschuh
CSB
2005
IEEE
125views Bioinformatics» more  CSB 2005»
14 years 2 months ago
On Optimizing Distance-Based Similarity Search for Biological Databases
Similarity search leveraging distance-based index structures is increasingly being used for both multimedia and biological database applications. We consider distance-based indexi...
Rui Mao, Weijia Xu, Smriti R. Ramakrishnan, Glen N...
BIBE
2003
IEEE
183views Bioinformatics» more  BIBE 2003»
14 years 2 months ago
Effective Indexing and Filtering for Similarity Search in Large Biosequence Databases
We present a multi-dimensional indexing approach for fast sequence similarity search in DNA and protein databases. In particular, we propose effective transformations of subsequen...
Ozgur Ozturk, Hakan Ferhatosmanoglu
BMCBI
2005
92views more  BMCBI 2005»
13 years 9 months ago
FIGENIX: Intelligent automation of genomic annotation: expertise integration in a new software platform
Background: Two of the main objectives of the genomic and post-genomic era are to structurally and functionally annotate genomes which consists of detecting genes' position a...
Philippe Gouret, Vérane Vitiello, Nathalie ...
BMCBI
2010
133views more  BMCBI 2010»
13 years 6 months ago
Initial steps towards a production platform for DNA sequence analysis on the grid
Background: Bioinformatics is confronted with a new data explosion due to the availability of high throughput DNA sequencers. Data storage and analysis becomes a problem on local ...
Angela C. M. Luyf, Barbera D. C. van Schaik, Miche...