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BIOINFORMATICS
1998
66views more  BIOINFORMATICS 1998»
13 years 7 months ago
Hidden Markov models for detecting remote protein homologies
Kevin Karplus, Christian Barrett, Richard Hughey
BMCBI
2008
138views more  BMCBI 2008»
13 years 7 months ago
Application of nonnegative matrix factorization to improve profile-profile alignment features for fold recognition and remote ho
Background: Nonnegative matrix factorization (NMF) is a feature extraction method that has the property of intuitive part-based representation of the original features. This uniqu...
Inkyung Jung, Jaehyung Lee, Soo-Young Lee, Dongsup...
BMCBI
2005
119views more  BMCBI 2005»
13 years 7 months ago
The distance-profile representation and its application to detection of distantly related protein families
Background: Detecting homology between remotely related protein families is an important problem in computational biology since the biological properties of uncharacterized protei...
Chin-Jen Ku, Golan Yona
BMCBI
2006
180views more  BMCBI 2006»
13 years 7 months ago
Building multiclass classifiers for remote homology detection and fold recognition
Motivation Protein remote homology prediction and fold recognition are central problems in computational biology. Supervised learning algorithms based on support vector machines a...
Huzefa Rangwala, George Karypis
NAR
2007
152views more  NAR 2007»
13 years 7 months ago
COMPASS server for remote homology inference
COMPASS is a method for homology detection and local alignment construction based on the comparison of multiple sequence alignments (MSAs). The method derives numerical profiles f...
Ruslan Sadreyev, Ming Tang, Bong-Hyun Kim, Nick V....