44 search results - page 6 / 9 » A Discriminative Framework for Detecting Remote Protein Homo... |
BMCBI
2010
13 years 7 months ago
2010
Background: Profile hidden Markov models (profile-HMMs) are sensitive tools for remote protein homology detection, but the main scoring algorithms, Viterbi or Forward, require con...
BMCBI
2006
13 years 7 months ago
2006
Background: The functional annotation of proteins relies on published information concerning their close and remote homologues in sequence databases. Evidence for remote sequence ...
NIPS
2008
13 years 9 months ago
2008
We present a new family of linear time algorithms based on sufficient statistics for string comparison with mismatches under the string kernels framework. Our algorithms improve t...
ISMB
2000
13 years 8 months ago
2000
Knowing the number of residue contacts in a protein is crucial for deriving constraints useful in modeling protein folding, protein structure, and/or scoring remote homology searc...
BMCBI
2010
13 years 7 months ago
2010
Background: The rapid development of structural genomics has resulted in many "unknown function" proteins being deposited in Protein Data Bank (PDB), thus, the functiona...