Background: Predicting a protein's structural or functional class from its amino acid sequence or structure is a fundamental problem in computational biology. Recently, there...
Iain Melvin, Jason Weston, Christina S. Leslie, Wi...
Background: Exon arrays provide a way to measure the expression of different isoforms of genes in an organism. Most of the procedures to deal with these arrays are focused on gene...
We present a new semi-supervised training procedure for conditional random fields (CRFs) that can be used to train sequence segmentors and labelers from a combination of labeled a...
Feng Jiao, Shaojun Wang, Chi-Hoon Lee, Russell Gre...
More and more proteins have been observed to display functions through intrinsic disorder. Such structurally flexible regions are shown to play important roles in biological proces...
Chung-Tsai Su, Tong-Ming Hsu, Chien-Yu Chen, Yu-Ye...
In this paper, we present a graphical model for protein secondary structure prediction. This model extends segmental semi-Markov models (SSMM) to exploit multiple sequence alignme...