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NIPS
2008
13 years 9 months ago
Tighter Bounds for Structured Estimation
Large-margin structured estimation methods minimize a convex upper bound of loss functions. While they allow for efficient optimization algorithms, these convex formulations are n...
Olivier Chapelle, Chuong B. Do, Quoc V. Le, Alexan...
EVOW
2004
Springer
13 years 11 months ago
Evolving Regular Expression-Based Sequence Classifiers for Protein Nuclear Localisation
A number of bioinformatics tools use regular expression (RE) matching to locate protein or DNA sequence motifs that have been discovered by researchers in the laboratory. For exam...
Amine Heddad, Markus Brameier, Robert M. MacCallum
BMCBI
2010
117views more  BMCBI 2010»
13 years 7 months ago
Beyond rotamers: a generative, probabilistic model of side chains in proteins
Background: Accurately covering the conformational space of amino acid side chains is essential for important applications such as protein design, docking and high resolution stru...
Tim Harder, Wouter Boomsma, Martin Paluszewski, Je...
BMCBI
2010
112views more  BMCBI 2010»
13 years 7 months ago
Orientation-dependent backbone-only residue pair scoring functions for fixed backbone protein design
Background: Empirical scoring functions have proven useful in protein structure modeling. Most such scoring functions depend on protein side chain conformations. However, backbone...
Andrew J. Bordner
CEC
2009
IEEE
14 years 7 days ago
A novel EDAs based method for HP model protein folding
— The protein structure prediction (PSP) problem is one of the most important problems in computational biology. This paper proposes a novel Estimation of Distribution Algorithms...
Benhui Chen, Long Li, Jinglu Hu