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    BMCBI
    2010
    114views more  BMCBI 2010»
    Detecting variants with Metabolic Design, a new software tool to design probes for explorative functional DNA microarray develop
    13 years 7 months ago
    Detecting variants with Metabolic Design, a new software tool to design probes for explorative functional DNA microarray develop
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    Background: Microorganisms display vast diversity, and each one has its own set of genes, cell components and metabolic reactions. To assess their huge unexploited metabolic poten...
    Sébastien Terrat, Eric Peyretaillade, Olivi...
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    BMCBI
    2006
    142views more  BMCBI 2006»
    Correlated fragile site expression allows the identification of candidate fragile genes involved in immunity and associated with
    13 years 7 months ago
    Correlated fragile site expression allows the identification of candidate fragile genes involved in immunity and associated with
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    Background: Common fragile sites (cfs) are specific regions in the human genome that are particularly prone to genomic instability under conditions of replicative stress. Several ...
    Angela Re, Davide Corà, Alda Maria Puliti, ...
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    BMCBI
    2004
    139views more  BMCBI 2004»
    Resolution of large and small differences in gene expression using models for the Bayesian analysis of gene expression levels an
    13 years 7 months ago
    Resolution of large and small differences in gene expression using models for the Bayesian analysis of gene expression levels an
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    Background: The detection of small yet statistically significant differences in gene expression in spotted DNA microarray studies is an ongoing challenge. Meeting this challenge r...
    Jeffrey P. Townsend
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    BMCBI
    2010
    109views more  BMCBI 2010»
    Application of machine learning methods to histone methylation ChIP-Seq data reveals H4R3me2 globally represses gene expression
    13 years 7 months ago
    Application of machine learning methods to histone methylation ChIP-Seq data reveals H4R3me2 globally represses gene expression
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    Background: In the last decade, biochemical studies have revealed that epigenetic modifications including histone modifications, histone variants and DNA methylation form a comple...
    Xiaojiang Xu, Stephen Hoang, Marty W. Mayo, Stefan...
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    CIBB
    2009
    232views Artificial Intelligence» more  CIBB 2009»
    On the Use of Temporal Formal Logic to Model Gene Regulatory Networks
    13 years 8 months ago
    On the Use of Temporal Formal Logic to Model Gene Regulatory Networks
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    Modelling activities in molecular biology face the difficulty of prediction to link molecular knowledge with cell phenotypes. Even when the interaction graph between molecules is k...
    Gilles Bernot, Jean-Paul Comet
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