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» A Gene Network Model for Developing Cell Lineages
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BMCBI
2011
12 years 11 months ago
RegNetB: Predicting Relevant Regulator-Gene Relationships in Localized Prostate Tumor Samples
Background: A central question in cancer biology is what changes cause a healthy cell to form a tumor. Gene expression data could provide insight into this question, but it is dif...
Angel Alvarez, Peter J. Woolf
PSB
2004
13 years 9 months ago
Modeling Cellular Processes with Variational Bayesian Cooperative Vector Quantizer
Gene expression of a cell is controlled by sophisticated cellular processes. The capability of inferring the states of these cellular processes would provide insight into the mech...
Xinghua Lu, Milos Hauskrecht, Roger S. Day
IJBRA
2006
59views more  IJBRA 2006»
13 years 7 months ago
Predicting altered pathways using extendable scaffolds
: Many diseases, especially solid tumors, involve the disruption or deregulation of cellular processes. Most current work using gene expression and other high-throughput data, simp...
B. M. Broom, T. J. McDonnell, D. Subramanian
FM
2009
Springer
138views Formal Methods» more  FM 2009»
14 years 2 months ago
What Can Formal Methods Bring to Systems Biology?
This position paper argues that the operational modelling approaches from the formal methods community can be applied fruitfully within the systems biology domain. The results can ...
Nicola Bonzanni, K. Anton Feenstra, Wan Fokkink, E...
DAC
2007
ACM
13 years 11 months ago
Synthetic biology: from bacteria to stem cells
Synthetic biology is revolutionizing how we conceptualize and approach the engineering of biological systems. Recent advances in the field are allowing us to expand beyond the con...
Ron Weiss