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» A Gene Network Model for Developing Cell Lineages
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IJDMB
2011
129views more  IJDMB 2011»
12 years 11 months ago
Modelling gene and protein regulatory networks with Answer Set Programming
: Recently, many approaches to model regulatory networks have been proposed in the systems biology domain, however the task is far from being solved. In this paper we propose an an...
Timur Fayruzov, Jeroen Janssen, Dirk Vermeir, Chri...
CISIS
2010
IEEE
14 years 2 months ago
Gene Ontology Rewritten for Computing Gene Functional Similarity
Abstract—Discovery biological organisation of the cell in modules network is a challenging task. Currently, approaches based on a controlled vocabulary, as Gene Ontology, to iden...
Alessia Visconti, Francesca Cordero, Marco Botta, ...
DFG
2007
Springer
14 years 1 months ago
PointCloudXplore 2: Visual Exploration of 3D Gene Expression
: To better understand how developmental regulatory networks are defined in the genome sequence, the Berkeley Drosophila Transcription Network Project (BDNTP) has developed a suit...
Oliver Rübel, Gunther H. Weber, Min-Yu Huang,...
BIOCOMP
2006
13 years 9 months ago
Computational Inference of Compound-induced Anti-inflammatory Effects Across Time in an Adjuvant-induced Arthritis Rat Model
A number of diseases, such as arthritis and cardiovascular disorders impacting the lives of many people have strong inflammatory components. To elucidate the antiinflammatory mecha...
Jing Yu, Gabriel Helmlinger, Muriel Saulnier, Anna...
BMCBI
2010
133views more  BMCBI 2010»
13 years 7 months ago
Predicting enzyme targets for cancer drugs by profiling human Metabolic reactions in NCI-60 cell lines
Background: Drugs can influence the whole metabolic system by targeting enzymes which catalyze metabolic reactions. The existence of interactions between drugs and metabolic react...
Limin Li, Xiaobo Zhou, Wai-Ki Ching, Ping Wang