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BMCBI
2006
144views more  BMCBI 2006»
13 years 8 months ago
methBLAST and methPrimerDB: web-tools for PCR based methylation analysis
Background: DNA methylation plays an important role in development and tumorigenesis by epigenetic modification and silencing of critical genes. The development of PCR-based methy...
Filip Pattyn, Jasmien Hoebeeck, Piet Robbrecht, Ev...
BMCBI
2006
127views more  BMCBI 2006»
13 years 8 months ago
Construction of phylogenetic trees by kernel-based comparative analysis of metabolic networks
Background: To infer the tree of life requires knowledge of the common characteristics of each species descended from a common ancestor as the measuring criteria and a method to c...
Sok June Oh, Je-Gun Joung, Jeong Ho Chang, Byoung-...
BMCBI
2006
127views more  BMCBI 2006»
13 years 8 months ago
Using local gene expression similarities to discover regulatory binding site modules
Background: We present an approach designed to identify gene regulation patterns using sequence and expression data collected for Saccharomyces cerevisae. Our main goal is to rela...
Bartek Wilczynski, Torgeir R. Hvidsten, Andriy Kry...
BMCBI
2006
113views more  BMCBI 2006»
13 years 8 months ago
GibbsST: a Gibbs sampling method for motif discovery with enhanced resistance to local optima
Background: Computational discovery of transcription factor binding sites (TFBS) is a challenging but important problem of bioinformatics. In this study, improvement of a Gibbs sa...
Kazuhito Shida
CCR
2006
76views more  CCR 2006»
13 years 8 months ago
Secure distributed data-mining and its application to large-scale network measurements
The rapid growth of the Internet over the last decade has been startling. However, efforts to track its growth have often fallen afoul of bad data -- for instance, how much traffi...
Matthew Roughan, Yin Zhang
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