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BMCBI
2008
124views more  BMCBI 2008»
13 years 7 months ago
A probe-treatment-reference (PTR) model for the analysis of oligonucleotide expression microarrays
Background: Microarray pre-processing usually consists of normalization and summarization. Normalization aims to remove non-biological variations across different arrays. The norm...
Huanying Ge, Chao Cheng, Lei M. Li
BIRD
2008
Springer
141views Bioinformatics» more  BIRD 2008»
13 years 9 months ago
Nested q-Partial Graphs for Genetic Network Inference from "Small n, Large p" Microarray Data
Abstract. Gaussian graphical models are widely used to tackle the important and challenging problem of inferring genetic regulatory networks from expression data. These models have...
Kevin Kontos, Gianluca Bontempi
NAR
2007
97views more  NAR 2007»
13 years 7 months ago
Gene Aging Nexus: a web database and data mining platform for microarray data on aging
The recent development of microarray technology provided unprecedented opportunities to understand the genetic basis of aging. So far, many microarray studies have addressed aging...
Fei Pan, Chi-Hsien Chiu, Sudip Pulapura, Michael R...
BIOCOMP
2009
13 years 8 months ago
Inferring Gene Regulatory Networks from Asynchronous Microarray Data
Modern approaches to treating genetic disorders, cancers and even epidemics rely on a detailed understanding of the underlying gene signaling network. Previous work has used time s...
David Oviatt, Mark J. Clement, Quinn Snell, Kennet...
BMCBI
2004
180views more  BMCBI 2004»
13 years 7 months ago
Noise filtering and nonparametric analysis of microarray data underscores discriminating markers of oral, prostate, lung, ovaria
Background: A major goal of cancer research is to identify discrete biomarkers that specifically characterize a given malignancy. These markers are useful in diagnosis, may identi...
Virginie M. Aris, Michael J. Cody, Jeff Cheng, Jam...