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CORR
2004
Springer
133views Education» more  CORR 2004»
13 years 7 months ago
Information theory, multivariate dependence, and genetic network inference
We define the concept of dependence among multiple variables using maximum entropy techniques and introduce a graphical notation to denote the dependencies. Direct inference of in...
Ilya Nemenman
CEC
2011
IEEE
12 years 7 months ago
Inferring transcriptional regulators for sets of co-expressed genes by multi-objective evolutionary optimization
Abstract—Higher organisms are able to respond to continuously changing external conditions by transducing cellular signals into specific regulatory programs, which control gene ...
Adrian Schröder, Clemens Wrzodek, Johannes Wo...
BIBE
2007
IEEE
115views Bioinformatics» more  BIBE 2007»
14 years 2 months ago
Semiparametric RMA Background-Correction for Oligonucleotide Arrays
—Microarray technology has provided an opportunity to simultaneously monitor the expression levels of a large number of genes in response to intentional perturbations. A necessar...
Ionut Bebu, Françoise Seillier-Moiseiwitsch...
ALMOB
2007
111views more  ALMOB 2007»
13 years 8 months ago
Transcriptional regulatory network discovery via multiple method integration: application to e. coli K12
Motivation: Transcriptional regulatory network (TRN) discovery from one method (e.g. microarray analysis, gene ontology, phylogenic similarity) does not seem feasible due to lack ...
Jingjun Sun, Kagan Tuncay, Alaa Abi Haidar, Lisa E...
BMCBI
2006
203views more  BMCBI 2006»
13 years 7 months ago
Independent component analysis reveals new and biologically significant structures in micro array data
Background: An alternative to standard approaches to uncover biologically meaningful structures in micro array data is to treat the data as a blind source separation (BSS) problem...
Attila Frigyesi, Srinivas Veerla, David Lindgren, ...