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BMCBI
2006
198views more  BMCBI 2006»
13 years 9 months ago
Gene selection and classification of microarray data using random forest
Background: Selection of relevant genes for sample classification is a common task in most gene expression studies, where researchers try to identify the smallest possible set of ...
Ramón Díaz-Uriarte, Sara Alvarez de ...
BMCBI
2006
119views more  BMCBI 2006»
13 years 9 months ago
A methodology for the structural and functional analysis of signaling and regulatory networks
Background: Structural analysis of cellular interaction networks contributes to a deeper understanding of network-wide interdependencies, causal relationships, and basic functiona...
Steffen Klamt, Julio Saez-Rodriguez, Jonathan A. L...
GPEM
2008
128views more  GPEM 2008»
13 years 9 months ago
Coevolutionary bid-based genetic programming for problem decomposition in classification
In this work a cooperative, bid-based, model for problem decomposition is proposed with application to discrete action domains such as classification. This represents a significan...
Peter Lichodzijewski, Malcolm I. Heywood
BMCBI
2006
195views more  BMCBI 2006»
13 years 9 months ago
Hubs of knowledge: using the functional link structure in Biozon to mine for biologically significant entities
Background: Existing biological databases support a variety of queries such as keyword or definition search. However, they do not provide any measure of relevance for the instance...
Paul Shafer, Timothy Isganitis, Golan Yona
BMCBI
2006
85views more  BMCBI 2006»
13 years 9 months ago
Use of physiological constraints to identify quantitative design principles for gene expression in yeast adaptation to heat shoc
Background: Understanding the relationship between gene expression changes, enzyme activity shifts, and the corresponding physiological adaptive response of organisms to environme...
Ester Vilaprinyó, Rui Alves, Albert Sorriba...
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