Abstract. An important unsolved problem in structural bioinformatics is that of protein structure prediction (PSP), the reconstruction of a biologically plausible three-dimensional...
Stefano Teso, Cristina Di Risio, Andrea Passerini,...
Weintroduce a parallel approach, "DT-SELECT," for selecting features used by inductive learning algorithms to predict protein secondary structure. DT-SELECTis able to ra...
Determining the number and location of disulfide bonds within a protein provide valuable insight into the protein’s three-dimensional structure. Purely computational methods tha...
Timothy Lee, Rahul Singh, Ten-Yang Yen, Bruce Mach...
Protein fold recognition is a key step towards inferring the tertiary structures from amino-acid sequences. Complex folds such as those consisting of interacting structural repeat...
Background: Certain protein families are highly conserved across distantly related organisms and belong to large and functionally diverse superfamilies. The patterns of conservati...