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» A Graph-Based Semi-supervised Algorithm for Protein Function...
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BMCBI
2006
129views more  BMCBI 2006»
13 years 7 months ago
Improved alignment quality by combining evolutionary information, predicted secondary structure and self-organizing maps
Background: Protein sequence alignment is one of the basic tools in bioinformatics. Correct alignments are required for a range of tasks including the derivation of phylogenetic t...
Tomas Ohlson, Varun Aggarwal, Arne Elofsson, Rober...
BIBM
2008
IEEE
217views Bioinformatics» more  BIBM 2008»
14 years 1 months ago
Combining Hierarchical Inference in Ontologies with Heterogeneous Data Sources Improves Gene Function Prediction
The study of gene function is critical in various genomic and proteomic fields. Due to the availability of tremendous amounts of different types of protein data, integrating thes...
Xiaoyu Jiang, Naoki Nariai, Martin Steffen, Simon ...
BMCBI
2008
121views more  BMCBI 2008»
13 years 7 months ago
iRefIndex: A consolidated protein interaction database with provenance
Background: Interaction data for a given protein may be spread across multiple databases. We set out to create a unifying index that would facilitate searching for these data and ...
Sabry Razick, George Magklaras, Ian M. Donaldson
BMCBI
2006
144views more  BMCBI 2006»
13 years 7 months ago
Development and implementation of an algorithm for detection of protein complexes in large interaction networks
Background: After complete sequencing of a number of genomes the focus has now turned to proteomics. Advanced proteomics technologies such as two-hybrid assay, mass spectrometry e...
Md. Altaf-Ul-Amin, Yoko Shinbo, Kenji Mihara, Ken ...
BMCBI
2008
131views more  BMCBI 2008»
13 years 7 months ago
Modifying the DPClus algorithm for identifying protein complexes based on new topological structures
Background: Identification of protein complexes is crucial for understanding principles of cellular organization and functions. As the size of protein-protein interaction set incr...
Min Li, Jianer Chen, Jianxin Wang, Bin Hu, Gang Ch...