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BIOINFORMATICS
2010
138views more  BIOINFORMATICS 2010»
13 years 7 months ago
Robust unmixing of tumor states in array comparative genomic hybridization data
Motivation: Tumorigenesis is an evolutionary process by which tumor cells acquire sequences of mutations leading to increased growth, invasiveness, and eventually metastasis. It i...
David Tolliver, Charalampos E. Tsourakakis, Ayshwa...
CSB
2005
IEEE
182views Bioinformatics» more  CSB 2005»
14 years 1 months ago
Bacterial Whole Genome Phylogeny Using Proteome Comparison and Optimal Reversal Distance
Traditional phylogenetic tree reconstruction is based on point mutations of a single gene. This approach is hardly suitable for genomes whose genes are almost identical and hardly...
Noppadon Khiripet
JCB
2006
124views more  JCB 2006»
13 years 7 months ago
The Average Common Substring Approach to Phylogenomic Reconstruction
We describe a novel method for efficient reconstruction of phylogenetic trees, based on sequences of whole genomes or proteomes, whose lengths may greatly vary. The core of our me...
Igor Ulitsky, David Burstein, Tamir Tuller, Benny ...
PR
2006
76views more  PR 2006»
13 years 7 months ago
A pattern recognition-based approach for phylogenetic network construction with constrained recombination
The tree representation of evolutionary relationship oversimplifies the view of the process of evolution as it cannot take into account the events such as horizontal gene transfer...
M. A. H. Zahid, Ankush Mittal, Ramesh Chandra Josh...
AAAI
2010
13 years 8 months ago
Genome Rearrangement: A Planning Approach
Evolutionary trees of species can be reconstructed by pairwise comparison of their entire genomes. Such a comparison can be quantified by determining the number of events that cha...
Tansel Uras, Esra Erdem