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CMSB
2008
Springer
13 years 10 months ago
A Model Checking Approach to the Parameter Estimation of Biochemical Pathways
Model checking has historically been an important tool to verify models of a wide variety of systems. Typically a model has to exhibit certain properties to be classed `acceptable&...
Robin Donaldson, David Gilbert
UMC
2000
14 years 4 days ago
In-vitro Transcriptional Circuits
The structural similarity of neural networks and genetic regulatory networks to digital circuits, and hence to each other, was noted from the very beginning of their study [1, 2]....
Erik Winfree
CEC
2010
IEEE
13 years 3 months ago
Parameter estimation with term-wise decomposition in biochemical network GMA models by hybrid regularized Least Squares-Particle
High-throughput analytical techniques such as nuclear magnetic resonance, protein kinase phosphorylation, and mass spectroscopic methods generate time dense profiles of metabolites...
Prospero C. Naval, Luis G. Sison, Eduardo R. Mendo...
ARCS
2005
Springer
14 years 2 months ago
The Bio-Chemical Information Processing Metaphor as a Programming Paradigm for Organic Computing
All known life forms process information on a molecular level. This kind of chemical information processing is known to be robust, self-organizing, adaptive, decentralized, asynch...
Peter Dittrich
CDC
2009
IEEE
133views Control Systems» more  CDC 2009»
14 years 1 months ago
Kinetic perturbations as robustness analysis tool for biochemical reaction networks
— Models of biochemical reaction networks can be decomposed into a stoichiometric part and a kinetic part. The stoichiometric part describes the structural mass flows while the ...
Steffen Waldherr, Frank Allgöwer, Elling W. J...