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BMCBI
2010
178views more  BMCBI 2010»
13 years 8 months ago
Applications of a formal approach to decipher discrete genetic networks
Background: A growing demand for tools to assist the building and analysis of biological networks exists in systems biology. We argue that the use of a formal approach is relevant...
Fabien Corblin, Eric Fanchon, Laurent Trilling
BMCBI
2006
172views more  BMCBI 2006»
13 years 8 months ago
BioWarehouse: a bioinformatics database warehouse toolkit
Background: This article addresses the problem of interoperation of heterogeneous bioinformatics databases. Results: We introduce BioWarehouse, an open source toolkit for construc...
Thomas J. Lee, Yannick Pouliot, Valerie Wagner, Pr...
VRML
2004
ACM
14 years 2 months ago
PathSim visualizer: an Information-Rich Virtual Environment framework for systems biology
Increasingly, biology researchers and medical practitioners are using computational tools to model and analyze dynamic systems across scales from the macro to the cellular to the ...
Nicholas F. Polys, Doug A. Bowman, Chris North, Re...
CDC
2008
IEEE
140views Control Systems» more  CDC 2008»
14 years 3 months ago
Model discrimination of polynomial systems via stochastic inputs
— Systems biologists are often faced with competing models for a given experimental system. Unfortunately, performing experiments can be time-consuming and expensive. Therefore, ...
Daniel Georgiev, Eric Klavins
BMCBI
2006
175views more  BMCBI 2006»
13 years 8 months ago
Parameter estimation for stiff equations of biosystems using radial basis function networks
Background: The modeling of dynamic systems requires estimating kinetic parameters from experimentally measured time-courses. Conventional global optimization methods used for par...
Yoshiya Matsubara, Shinichi Kikuchi, Masahiro Sugi...