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BMCBI
2010
190views more  BMCBI 2010»
13 years 8 months ago
APIS: accurate prediction of hot spots in protein interfaces by combining protrusion index with solvent accessibility
Background: It is well known that most of the binding free energy of protein interaction is contributed by a few key hot spot residues. These residues are crucial for understandin...
Jun-Feng Xia, Xing-Ming Zhao, Jiangning Song, De-S...
BMCBI
2010
177views more  BMCBI 2010»
13 years 8 months ago
Modular composition predicts kinase/substrate interactions
Background: Phosphorylation events direct the flow of signals and metabolites along cellular protein networks. Current annotations of kinase-substrate binding events are far from ...
Yichuan Liu, Aydin Tozeren
BMCBI
2006
99views more  BMCBI 2006»
13 years 8 months ago
A proposed metric for assessing the measurement quality of individual microarrays
Background: High-density microarray technology is increasingly applied to study gene expression levels on a large scale. Microarray experiments rely on several critical steps that...
Kyoungmi Kim, Grier P. Page, T. Mark Beasley, Step...
GFKL
2005
Springer
114views Data Mining» more  GFKL 2005»
14 years 2 months ago
Attribute-aware Collaborative Filtering
One of the key challenges in large information systems such as online shops and digital libraries is to discover the relevant knowledge from the enormous volume of information. Rec...
Karen H. L. Tso, Lars Schmidt-Thieme
IPPS
2003
IEEE
14 years 1 months ago
Simulation of Dynamic Data Replication Strategies in Data Grids
Data Grids provide geographically distributed resources for large-scale data-intensive applications that generate large data sets. However, ensuring efficient access to such huge...
Houda Lamehamedi, Zujun Shentu, Boleslaw K. Szyman...