Background: It is well known that most of the binding free energy of protein interaction is contributed by a few key hot spot residues. These residues are crucial for understandin...
Background: Phosphorylation events direct the flow of signals and metabolites along cellular protein networks. Current annotations of kinase-substrate binding events are far from ...
Background: High-density microarray technology is increasingly applied to study gene expression levels on a large scale. Microarray experiments rely on several critical steps that...
Kyoungmi Kim, Grier P. Page, T. Mark Beasley, Step...
One of the key challenges in large information systems such as online shops and digital libraries is to discover the relevant knowledge from the enormous volume of information. Rec...
Data Grids provide geographically distributed resources for large-scale data-intensive applications that generate large data sets. However, ensuring efficient access to such huge...
Houda Lamehamedi, Zujun Shentu, Boleslaw K. Szyman...