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BMCBI
2010
170views more  BMCBI 2010»
13 years 9 months ago
Integrative analysis of gene expression and copy number alterations using canonical correlation analysis
Background: With the rapid development of new genetic measurement methods, several types of genetic alterations can be quantified in a high-throughput manner. While the initial fo...
Charlotte Soneson, Henrik Lilljebjörn, Thoas ...
BMCBI
2010
158views more  BMCBI 2010»
13 years 9 months ago
A Bayesian network approach to feature selection in mass spectrometry data
Background: Time-of-flight mass spectrometry (TOF-MS) has the potential to provide non-invasive, high-throughput screening for cancers and other serious diseases via detection of ...
Karl W. Kuschner, Dariya I. Malyarenko, William E....
BMCBI
2004
141views more  BMCBI 2004»
13 years 9 months ago
Estimates of statistical significance for comparison of individual positions in multiple sequence alignments
Background: Profile-based analysis of multiple sequence alignments (MSA) allows for accurate comparison of protein families. Here, we address the problems of detecting statistical...
Ruslan Sadreyev, Nick V. Grishin
CPM
2000
Springer
141views Combinatorics» more  CPM 2000»
14 years 23 days ago
A Lower Bound for the Breakpoint Phylogeny Problem
Breakpoint phylogenies methods have been shown to be an effective way to extract phylogenetic information from gene order data. Currently, the only practical breakpoint phylogeny a...
David Bryant
JDFP
2006
139views more  JDFP 2006»
13 years 9 months ago
Discovering Hidden Evidence
Over the past decade, the advancement of a myriad of methods, techniques and technologies to conceal digital evidence and covertly communicate have increased at an alarming rate. I...
Chet Hosmer