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RECOMB
2010
Springer
13 years 9 months ago
naiveBayesCall: An Efficient Model-Based Base-Calling Algorithm for High-Throughput Sequencing
Immense amounts of raw instrument data (i.e., images of fluorescence) are currently being generated using ultra high-throughput sequencing platforms. An important computational cha...
Wei-Chun Kao, Yun S. Song
IJIT
2004
13 years 9 months ago
Computing Entropy for Ortholog Detection
Abstract-- Biological sequences from different species are called orthologs if they evolved from a sequence of a common ancestor species and they have the same biological function....
Hsing-Kuo Pao, John Case
BMCBI
2010
165views more  BMCBI 2010»
13 years 7 months ago
Bayesian integrated modeling of expression data: a case study on RhoG
Background: DNA microarrays provide an efficient method for measuring activity of genes in parallel and even covering all the known transcripts of an organism on a single array. T...
Rashi Gupta, Dario Greco, Petri Auvinen, Elja Arja...
BMCBI
2010
109views more  BMCBI 2010»
13 years 7 months ago
Structural alphabets derived from attractors in conformational space
Background: The hierarchical and partially redundant nature of protein structures justifies the definition of frequently occurring conformations of short fragments as `states'...
Alessandro Pandini, Arianna Fornili, Jens Kleinjun...
BMCBI
2008
106views more  BMCBI 2008»
13 years 7 months ago
A machine vision system for automated non-invasive assessment of cell viability via dark field microscopy, wavelet feature selec
Background: Cell viability is one of the basic properties indicating the physiological state of the cell, thus, it has long been one of the major considerations in biotechnologica...
Ning Wei, Erwin Flaschel, Karl Friehs, Tim W. Natt...