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BMCBI
2010
136views more  BMCBI 2010»
13 years 7 months ago
Protein structure analysis of mutations causing inheritable diseases. An e-Science approach with life scientist friendly interfa
Background: Many newly detected point mutations are located in protein-coding regions of the human genome. Knowledge of their effects on the protein's 3D structure provides i...
Hanka Venselaar, Tim A. H. te Beek, Remko K. P. Ku...
BMCBI
2008
160views more  BMCBI 2008»
13 years 7 months ago
VariVis: a visualisation toolkit for variation databases
Background: With the completion of the Human Genome Project and recent advancements in mutation detection technologies, the volume of data available on genetic variations has rise...
Timothy D. Smith, Richard G. H. Cotton
BMCBI
2008
138views more  BMCBI 2008»
13 years 7 months ago
Using neural networks and evolutionary information in decoy discrimination for protein tertiary structure prediction
Background: We present a novel method of protein fold decoy discrimination using machine learning, more specifically using neural networks. Here, decoy discrimination is represent...
Ching-Wai Tan, David T. Jones
BMCBI
2008
116views more  BMCBI 2008»
13 years 7 months ago
Structuring an event ontology for disease outbreak detection
Background: This paper describes the design of an event ontology being developed for application in the machine understanding of infectious disease-related events reported in natu...
Ai Kawazoe, Hutchatai Chanlekha, Mika Shigematsu, ...
DCG
2008
118views more  DCG 2008»
13 years 7 months ago
General-Dimensional Constrained Delaunay and Constrained Regular Triangulations, I: Combinatorial Properties
Two-dimensional constrained Delaunay triangulations are geometric structures that are popular for interpolation and mesh generation because they respect the shapes of planar domai...
Jonathan Richard Shewchuk
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