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BMCBI
2011
15 years 6 days ago
Assessing the benefits of using mate-pairs to resolve repeats in de novo short-read prokaryotic assemblies
Background: Next-generation sequencing technologies allow genomes to be sequenced more quickly and less expensively than ever before. However, as sequencing technology has improve...
Joshua Wetzel, Carl Kingsford, Mihai Pop
BMCBI
2011
15 years 6 days ago
SNP-based pathway enrichment analysis for genome-wide association studies
Background: Recently we have witnessed a surge of interest in using genome-wide association studies (GWAS) to discover the genetic basis of complex diseases. Many genetic variatio...
Lingjie Weng, Fabio Macciardi, Aravind Subramanian...
BMCBI
2011
15 years 6 days ago
PhyloSim - Monte Carlo simulation of sequence evolution in the R statistical computing environment
Background: The Monte Carlo simulation of sequence evolution is routinely used to assess the performance of phylogenetic inference methods and sequence alignment algorithms. Progr...
Botond Sipos, Tim Massingham, Gregory E. Jordan, N...
BMCBI
2011
15 years 6 days ago
SNPPicker: High quality tag SNP selection across multiple populations
Background: Linkage Disequilibrium (LD) bin-tagging algorithms identify a reduced set of tag SNPs that can capture the genetic variation in a population without genotyping every s...
Hugues Sicotte, David N. Rider, Gregory A. Poland,...
CORR
2011
Springer
174views Education» more  CORR 2011»
15 years 6 days ago
Physical expander in Virtual Tree Overlay
Abstract. In this paper, we propose a new construction of constantdegree expanders motivated by their application in P2P overlay networks and in particular in the design of robust ...
Taisuke Izumi, Maria Potop-Butucaru, Mathieu Valer...
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