342 search results - page 18 / 69 » A New Alignment-Independent Algorithm for Clustering Protein... |
BMCBI
2010
13 years 7 months ago
2010
Background: Prediction of protein structural classes (a, b, a + b and a/b) from amino acid sequences is of great importance, as it is beneficial to study protein function, regulat...
BMCBI
2008
13 years 7 months ago
2008
Background: Classification of protein sequences is a central problem in computational biology. Currently, among computational methods discriminative kernel-based approaches provid...
CIBCB
2005
IEEE
13 years 9 months ago
2005
IEEE
— We present an integrative method for clustering coregulated genes and elucidating their underlying regulatory mechanisms. We use multi-state partition functions and thermodynam...
BIBE
2008
IEEE
14 years 2 months ago
2008
IEEE
— The Smith-Waterman algorithm is a dynamic programming method for determining optimal local alignments between nucleotide or protein sequences. However, it suffers from quadrati...
SDM
2007
SIAM
13 years 9 months ago
2007
SIAM
In this paper, we explore the discriminating subsequencebased clustering problem. First, several effective optimization techniques are proposed to accelerate the sequence mining p...