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» A New Approach to Protein Structure Mining and Alignment
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BMCBI
2006
133views more  BMCBI 2006»
13 years 7 months ago
An integrated approach to the prediction of domain-domain interactions
Background: The development of high-throughput technologies has produced several large scale protein interaction data sets for multiple species, and significant efforts have been ...
Hyunju Lee, Minghua Deng, Fengzhu Sun, Ting Chen
BMCBI
2006
102views more  BMCBI 2006»
13 years 7 months ago
Prediction of protein structural class with Rough Sets
Background: A new method for the prediction of protein structural classes is constructed based on Rough Sets algorithm, which is a rule-based data mining method. Amino acid compos...
Youfang Cao, Shi Liu, Lida Zhang, Jie Qin, Jiang W...
WABI
2005
Springer
109views Bioinformatics» more  WABI 2005»
14 years 25 days ago
Optimal Protein Threading by Cost-Splitting
Abstract. In this paper, we use integer programming approach for solving a hard combinatorial optimization problem, namely protein threading. For this sequence-to-structure alignme...
Philippe Veber, Nicola Yanev, Rumen Andonov, Vince...
BIB
2006
141views more  BIB 2006»
13 years 7 months ago
Statistical significance in biological sequence analysis
One of the major goals of computational sequence analysis is to find sequence similarities, which could serve as evidence of structural and functional conservation, as well as of ...
Alexander Yu. Mitrophanov, Mark Borodovsky
BIBM
2010
IEEE
156views Bioinformatics» more  BIBM 2010»
13 years 5 months ago
Truncation of protein sequences for fast profile alignment with application to subcellular localization
We have recently found that the computation time of homology-based subcellular localization can be substantially reduced by aligning profiles up to the cleavage site positions of s...
Man-Wai Mak, Wei Wang, Sun-Yuan Kung