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» A New Approach to Protein Structure Mining and Alignment
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BMCBI
2010
136views more  BMCBI 2010»
13 years 8 months ago
Protein structure analysis of mutations causing inheritable diseases. An e-Science approach with life scientist friendly interfa
Background: Many newly detected point mutations are located in protein-coding regions of the human genome. Knowledge of their effects on the protein's 3D structure provides i...
Hanka Venselaar, Tim A. H. te Beek, Remko K. P. Ku...
BMCBI
2006
140views more  BMCBI 2006»
13 years 8 months ago
MACSIMS : multiple alignment of complete sequences information management system
Background: In the post-genomic era, systems-level studies are being performed that seek to explain complex biological systems by integrating diverse resources from fields such as...
Julie D. Thompson, Arnaud Muller, Andrew M. Waterh...
BMCBI
2005
155views more  BMCBI 2005»
13 years 8 months ago
Mining protein function from text using term-based support vector machines
Background: Text mining has spurred huge interest in the domain of biology. The goal of the BioCreAtIvE exercise was to evaluate the performance of current text mining systems. We...
Simon B. Rice, Goran Nenadic, Benjamin J. Stapley
ICDM
2007
IEEE
126views Data Mining» more  ICDM 2007»
14 years 2 months ago
Exploration of Link Structure and Community-Based Node Roles in Network Analysis
Communities are nodes in a network that are grouped together based on a common set of properties. While the communities and link structures are often thought to be in alignment, i...
Jerry Scripps, Pang-Ning Tan, Abdol-Hossein Esfaha...
ICDM
2005
IEEE
125views Data Mining» more  ICDM 2005»
14 years 2 months ago
Alternate Representation of Distance Matrices for Characterization of Protein Structure
The most suitable method for the automated classification of protein structures remains an open problem in computational biology. In order to classify a protein structure with an...
Keith Marsolo, Srinivasan Parthasarathy