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» A New Approach to Protein Structure Mining and Alignment
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GEOS
2007
Springer
14 years 2 months ago
Structure-Based Methods to Enhance Geospatial Ontology Alignment
In geospatial applications with heterogeneous classification schemes that describe related domains, an ontology-driven approach to data sharing and interoperability relies on the ...
William Sunna, Isabel F. Cruz
BMCBI
2006
150views more  BMCBI 2006»
13 years 8 months ago
Cluster analysis of protein array results via similarity of Gene Ontology annotation
Background: With the advent of high-throughput proteomic experiments such as arrays of purified proteins comes the need to analyse sets of proteins as an ensemble, as opposed to t...
Cheryl Wolting, C. Jane McGlade, David Tritchler
BMCBI
2005
100views more  BMCBI 2005»
13 years 8 months ago
EvDTree: structure-dependent substitution profiles based on decision tree classification of 3D environments
Background: Structure-dependent substitution matrices increase the accuracy of sequence alignments when the 3D structure of one sequence is known, and are successful e.g. in fold ...
Jean-Christophe Gelly, Laurent Chiche, Jér&...
BMCBI
2008
116views more  BMCBI 2008»
13 years 8 months ago
The combination approach of SVM and ECOC for powerful identification and classification of transcription factor
Background: Transcription factors (TFs) are core functional proteins which play important roles in gene expression control, and they are key factors for gene regulation network co...
Guangyong Zheng, Ziliang Qian, Qing Yang, Chaochun...
BMCBI
2008
103views more  BMCBI 2008»
13 years 8 months ago
Detection of protein catalytic residues at high precision using local network properties
Background: Identifying the active site of an enzyme is a crucial step in functional studies. While protein sequences and structures can be experimentally characterized, determini...
Patrick Slama, Ioannis Filippis, Michael Lappe