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BMCBI
2005
113views more  BMCBI 2005»
13 years 9 months ago
Normal uniform mixture differential gene expression detection for cDNA microarrays
Background: One of the primary tasks in analysing gene expression data is finding genes that are differentially expressed in different samples. Multiple testing issues due to the ...
Nema Dean, Adrian E. Raftery
BMCBI
2005
85views more  BMCBI 2005»
13 years 9 months ago
Processing methods for differential analysis of LC/MS profile data
Background: Liquid chromatography coupled to mass spectrometry (LC/MS) has been widely used in proteomics and metabolomics research. In this context, the technology has been incre...
Mikko Katajamaa, Matej Oresic
BMCBI
2005
107views more  BMCBI 2005»
13 years 9 months ago
An edit script for taxonomic classifications
Abstract. Taxonomy provides one of the most powerful ways to navigate sequence data bases but currently, users are forced to formulate queries according to a single taxonomic class...
Roderic D. M. Page, Gabriel Valiente
BMCBI
2005
106views more  BMCBI 2005»
13 years 9 months ago
SIMPROT: Using an empirically determined indel distribution in simulations of protein evolution
Background: General protein evolution models help determine the baseline expectations for the evolution of sequences, and they have been extensively useful in sequence analysis an...
Andy Pang, Andrew D. Smith, Paulo A. S. Nuin, Elis...
BMCBI
2005
82views more  BMCBI 2005»
13 years 9 months ago
Quality assessment of microarrays: Visualization of spatial artifacts and quantitation of regional biases
Background: Quality-control is an important issue in the analysis of gene expression microarrays. One type of problem is regional bias, in which one region of a chip shows artifac...
Mark Reimers, John N. Weinstein
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