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BMCBI
2007
158views more  BMCBI 2007»
13 years 7 months ago
Penalized likelihood for sparse contingency tables with an application to full-length cDNA libraries
Background: The joint analysis of several categorical variables is a common task in many areas of biology, and is becoming central to systems biology investigations whose goal is ...
Corinne Dahinden, Giovanni Parmigiani, Mark C. Eme...
BMCBI
2007
176views more  BMCBI 2007»
13 years 7 months ago
Genome Expression Pathway Analysis Tool - Analysis and visualization of microarray gene expression data under genomic, proteomic
Background: Regulation of gene expression is relevant to many areas of biology and medicine, in the study of treatments, diseases, and developmental stages. Microarrays can be use...
Markus Weniger, Julia C. Engelmann, Jörg Schu...
BMCBI
2010
114views more  BMCBI 2010»
13 years 7 months ago
An integrative modular approach to systematically predict gene-phenotype associations
Background: Complex human diseases are often caused by multiple mutations, each of which contributes only a minor effect to the disease phenotype. To study the basis for these com...
Michael R. Mehan, Juan Nunez-Iglesias, Chao Dai, M...
BMCBI
2007
198views more  BMCBI 2007»
13 years 7 months ago
Correlation analysis reveals the emergence of coherence in the gene expression dynamics following system perturbation
Time course gene expression experiments are a popular means to infer co-expression. Many methods have been proposed to cluster genes or to build networks based on similarity measu...
Nicola Neretti, Daniel Remondini, Marc Tatar, John...
BMCBI
2010
100views more  BMCBI 2010»
13 years 7 months ago
Trimming of mammalian transcriptional networks using network component analysis
Background: Network Component Analysis (NCA) has been used to deduce the activities of transcription factors (TFs) from gene expression data and the TF-gene binding relationship. ...
Linh M. Tran, Daniel R. Hyduke, James C. Liao