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BMCBI
2010
97views more  BMCBI 2010»
13 years 7 months ago
Kinome-wide interaction modelling using alignment-based and alignment-independent approaches for kinase description and linear a
Background: Protein kinases play crucial roles in cell growth, differentiation, and apoptosis. Abnormal function of protein kinases can lead to many serious diseases, such as canc...
Maris Lapinsh, Jarl E. S. Wikberg
CIKM
2010
Springer
13 years 4 months ago
Regularization and feature selection for networked features
In the standard formalization of supervised learning problems, a datum is represented as a vector of features without prior knowledge about relationships among features. However, ...
Hongliang Fei, Brian Quanz, Jun Huan
JMLR
2012
11 years 9 months ago
Random Search for Hyper-Parameter Optimization
Grid search and manual search are the most widely used strategies for hyper-parameter optimization. This paper shows empirically and theoretically that randomly chosen trials are ...
James Bergstra, Yoshua Bengio
CSB
2004
IEEE
135views Bioinformatics» more  CSB 2004»
13 years 11 months ago
Selection of Patient Samples and Genes for Outcome Prediction
Gene expression profiles with clinical outcome data enable monitoring of disease progression and prediction of patient survival at the molecular level. We present a new computatio...
Huiqing Liu, Jinyan Li, Limsoon Wong
ISQED
2010
IEEE
141views Hardware» more  ISQED 2010»
14 years 2 months ago
Assessing chip-level impact of double patterning lithography
—Double patterning lithography (DPL) provides an attractive alternative or a supplementary method to enable the 32nm and 22nm process nodes, relative to costlier technology optio...
Kwangok Jeong, Andrew B. Kahng, Rasit Onur Topalog...