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» A New Method for DNA Microarray Image Segmentation
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BMCBI
2006
127views more  BMCBI 2006»
13 years 7 months ago
Improvement in the Reproducibility and Accuracy of DNA Microarray Quantification by Optimizing Hybridization Conditions
Background: DNA microarrays, which have been increasingly used to monitor mRNA transcripts at a global level, can provide detailed insight into cellular processes involved in resp...
Tao Han, Cathy D. Melvin, Leming M. Shi, William S...
BMCBI
2004
161views more  BMCBI 2004»
13 years 7 months ago
Three-parameter lognormal distribution ubiquitously found in cDNA microarray data and its application to parametric data treatme
Background: To cancel experimental variations, microarray data must be normalized prior to analysis. Where an appropriate model for statistical data distribution is available, a p...
Tomokazu Konishi
BMCBI
2005
113views more  BMCBI 2005»
13 years 7 months ago
Normal uniform mixture differential gene expression detection for cDNA microarrays
Background: One of the primary tasks in analysing gene expression data is finding genes that are differentially expressed in different samples. Multiple testing issues due to the ...
Nema Dean, Adrian E. Raftery
BMCBI
2006
85views more  BMCBI 2006»
13 years 7 months ago
On the statistical assessment of classifiers using DNA microarray data
Background: In this paper we present a method for the statistical assessment of cancer predictors which make use of gene expression profiles. The methodology is applied to a new d...
Nicola Ancona, Rosalia Maglietta, Ada Piepoli, Ann...
TITB
2008
109views more  TITB 2008»
13 years 7 months ago
Automatic Segmentation of High-Throughput RNAi Fluorescent Cellular Images
High throughput genome-wide RNAi screening is emerging as an essential tool to assist biologists in understanding complex cellular processes. The large number of images produced in...
Pingkun Yan, Xiaobo Zhou, Mubarak Shah, Stephen T....